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If you believe you could have celiac disease you will need to see
your physician immediately. The physician will likely have you take a
celiac disease blood test to confirm.
Celiac Disease (CD) is a digestive disorder that affects both
children and adults. This disease is life long and there is no cure.
Essentially when foods containing gluten are eaten the body has an
immune-mediated toxic reaction that causes damage to the small
intestine. This does not allow food to be properly absorbed. This
reaction will occur even if there is only a small amount of gluten
present.
Gluten is the protein in specific grains that are harmful to people
with celiac disease. You can find these harmful proteins in all forms
of wheat and related grains such as barley, triticale and rye. This
means ALL of these must be eliminated from the patient’s diet. One
important thing to understand is that celiac disease is not a food
allergy. It is an autoimmune disease. One out of one hundred thirty
three people in the United States have celiac disease.
Some symptoms of celiac disease are recurring bloating, gas and
abdominal pain, chronic diarrhea or constipation or both, unexplained
weight loss or weight gain, pale, foul-smelling stool, unexplained
anemia, bone and joint pain, behavioral changes, depression, vitamin K
deficiency, delayed growth, fatigue, weakness or lack of energy,
missed periods, infertility in male or female, spontaneous
miscarriages, canker sores inside the mouth and tooth discoloration or
loss of enamel.
To determine if you have celiac disease your physician will send
you for a celiac disease blood test. This specific antibody blood
test will screen for Endomysial antibody (EMA-IgA), tissue
transglutaminase antibody (tTG- LgA/lgG), anti-gliadin antibody
(AGA-lgG, AGA-lgA) and total serum lgA. If the patient is under the
age of two, tTG and EMA may not be present. If the results of the
blood test are inconclusive, then a small bowel biopsy may be
needed.
The blood tests only screen for the risk of celiac disease but it
isn’t a confirm or deny it’s presence. When blood tests and biopsy
are inconclusive, testing for HLA DQ2/DQ8 genes associated with celiac
disease may be performed. Celiac disease, being an autoimmune
disease, is the result of the interaction between genes and the
environment. HLA DQ2 and or DQ8 are necessary to develop Celiac
Disease. That does not mean it is present just that it is
possible.
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